I don’t like when the blog isn’t updated for several days, so here are some links to stuff I’ve encountered on the internet in the recent past:

i. Diabetic Autonomic Neuropathy. An overview article which covers a lot of ground; it has approximately 1000 citations and I believe it’s one of the most read articles published in Diabetes Care, a journal you incidentally should know about if you’re diabetic or are interested in diabetes.

ii. Also diabetes-related and closely related to the above paper: The EKG in Diabetes Mellitus. This article is particularly relevant to me because I had an EKG last week and will be told the results of it tomorrow where I have a doctor’s appointment – reading stuff like this first makes it easier to ask the right questions. I jokingly explained to a friend yesterday that if the results of that test come out a specific way, it will be much easier for me to make pension plans (meaning I’d most likely be dead long before the official retirement age – naturally I do not hope for that outcome to happen). I’ll also learn the results of the standard Hba-1c blood test – which is measured 3-4 times a year – as well as the annual urin-sample analysis to check for microalbuminuria (kidney damage). Also, cholesterol levels and triglycerides. So I’ll learn more from this check-up than I usually do. I hope everything is fine but there’s a reason why they perform tests like these; I have no way of knowing myself if there’s a problem here.

Anyway, a few quotes from the paper:

“Fibrotic changes, especially in the basal area of the left ventricle, have frequently been observed in diabetic patients, even when cardiac involvement is clinically not yet evident. […] The EURODIAB Insulin-Dependent Diabetes Mellitus Complications Study (EURODIAB IDDM)9 investigated 3250 type 1 diabetes patients with an average diabetes duration of >30 years; the prevalence of left ventricular hypertrophy was found to be 3 times greater than that reported in the general population of similar age. […] Baroreflex dysfunction and disturbed heart rate variability are the most commonly used methods to assess CAN [Cardiovascular autonomic neuropathy, US]. […]

Ong et al14 found the QTc to be shorter if patients had signs of neuropathy, although these patients’ heart rate was higher and their circadian patterns seemed to be preserved. Valensi et al15 found an unchanged QTc in mild neuropathy, although the circadian day/night QTc pattern was reversed. Pappachan et al16 expressed the view that the QTc interval can be used to diagnose CAN with reasonable sensitivity, specificity, and positive predictive value. Grossmann et al17 observed a prolonged QTc only in diabetic patients with CAN; late potentials were not recorded in any of these patients with CAN. CAN patients with prolonged variability in QTc, QT, or both had high incidence of sudden death.18 […]

Myocardial ischemia is more often painless in patients with diabetes mellitus.19 Resting ECG abnormalities20 as well as cardiac autonomic dysfunction21 were found to be predictors of silent ischemia in asymptomatic persons with T1D.

In otherwise healthy diabetic men during an average follow-up of 16 years, an abnormal and even an equivocal exercise ECG response was associated with a statistically significant high risk for all-cause and cardiac mortality and morbidity, independently of physical fitness and other traditional risk factors; fit men had a higher survival rate than did unfit men.22 [One more reason why I shouldn’t have that much trouble motivating myself to stay in shape.] […]

The early stage of diabetic cardiomyopathy may already be associated with a range of metabolic abnormalities and even with abnormalities in diastolic function. Frequently, no structural cardiac abnormalities can be identified at this stage; the often subtle ECG alterations may be our only way to diagnose early diabetic cardiomyopathy. […]


Even early in the course of diabetes mellitus, ECG alterations such as sinus tachycardia, long QTc, QT dispersion, changes in heart rate variability, ST-T changes, and left ventricular hypertrophy may be observed. ECG alterations help evaluate cardiac autonomic neuropathy and detect signs of myocardial ischemia even in asymptomatic patients. Prolonged myocardial fibrosis leads to diabetic cardiomyopathy, with peculiar ECG presentation. Electrocardiographic changes are already present in fetuses, children, and adolescents. The resting ECG, frequently complemented by exercise ECG, assists in cardiac screening of diabetic individuals and helps detect silent ischemia, assess prognosis, and predict mortality”

iii. Boredom Proneness: Its Relationship to Psychological- and Physical-Health Symptoms, by Sommers and Vodanovich.

“The relationship between boredom proneness and health-symptom reporting was examined. Undergraduate students (N 5 200) completed the Boredom Proneness Scale and the Hopkins Symptom Checklist. A multiple analysis of covariance indicated that individuals with high boredomproneness total scores reported significantly higher ratings on all five subscales of the Hopkins Symptom Checklist (Obsessive–Compulsive, Somatization, Anxiety, Interpersonal Sensitivity, and Depression). The results suggest that boredom proneness may be an important element to consider when assessing symptom reporting. Implications for determining the effects of boredom proneness on psychological- and physical-health symptoms, as well as the application in clinical settings, are discussed.”

I had no idea there was such a thing as a ‘Boredom Proneness Scale’! I found the literature overview in the beginning of the paper much more interesting than the study itself (one word: WEIRD). Judging from the reported results there, if you’re bored a lot and/or have a really boring job you may be well advised to do something about that – because being bored is associated with a lot of bad stuff:

“To date, the work on boredom proneness has focused on its association with negative affect, as well as problems in academic and work settings. For instance, significant positive relationships have been found between the tendency to experience boredom and depression, anxiety, hostility, anger, loneliness, and hopelessness (e.g., Ahmed, 1990; Farmer & Sundberg, 1986; Rupp & Vodanovich, 1997; Vodanovich, Verner, & Gilbride,
1991; Watt & Davis, 1991). Other researchers have reported boredom proneness to be related significantly to lower educational achievement, truancy rate, and poor work performance (e.g., Branton, 1970; Drory, 1982; Gardell, 1971; Maroldo, 1986; O’Hanlon, 1981; Robinson, 1975; Smith, 1981).

Limited work, however, has been devoted to investigating the association between boredom and psychological- and physical-health symptoms. Evidence for such a relationship can be inferred from studies reporting significant, positive correlations between boredom and substance abuse and eating disorders (e.g., Abramson & Stinson, 1977; Ganley, 1989; Johnston & O’Malley, 1986; Martin, 1989; Pascale & Sylvester, 1988).
Other researchers have established a connection between boredom and detrimental health effects in organizational settings. For instance, Smith, Cohen, and Stammerjohn (1981) found that workers in monotonous jobs reported more visual, musculoskeletal, and emotional-health complaints than those performing non-monotonous work. Samilova (1971) found that female Russian workers employed in repetitive tasks experienced higher incidence of health problems, including gastritis, peripheral neurological disorders, and joint, tendon, muscle, and cardiovascular disease, than workers in less-repetitive jobs. Ferguson (1973) found that telegraphists who complained of task monotony indicated a greater occurrence of physical-health problems, such as asthma, bronchitis, trunk myalgia, and hand tremors, as compared to other workers in less-monotonous positions.”

iv. Ideology, Motivated Reasoning, and Cognitive Reflection: An Experimental Study. I haven’t actually gotten around to reading this yet, but I bookmarked it for a reason; I probably will later during the week.

v. Media Use Among White, Black, Hispanic, and Asian American Children, by Rideout, Lauricella and Wartella. I’ve written about that stuff before but I haven’t written about this data. It’s survey data so it should be taken with a grain of salt. Even if it is, however, I think there’s some interesting information here. Some stuff from the report:

“Historically, scholars have been aware of differences in the amount of time that White and minority children spend with media, especially TV. But last year’s Generation M2 study indicated a large increase in the amount of time both Black and Hispanic youth are spending with media, to the point where they are consuming an average of 13 hours worth of media content a day (12:59 for Blacks and 13:00 for Hispanics), compared with about eight and a half hours (8:36) for White youth, a difference of about four and a half hours a day.” [my emphasis] […]

The biggest differences are in the amount of time spent with a TV (a difference of about one to two hours of TV a day between White and minority youth), music (a difference of about an hour a day), computers (up to an hour and a half difference), and video games (from 30 to 40 minutes difference).”

Here’s the ‘big picture’, click to view full size:

media expo

vi. I really, truly dislike (and that’s putting it mildly) the new format for the discover magazine blogs, but I really liked this post by Razib Khan. Then again it was posted before the switch. I like a lot of his stuff so I tend not to link to individual posts (I’d have to link to a lot of stuff…) but I figure I should remind you now and then that you should be reading his blog. Even if the new format sucks.


December 4, 2012 - Posted by | Cardiology, Data, Demographics, Diabetes, Medicine, Neurology, Papers, Personal, Psychology, Random stuff

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